Who Proposed the Theory of Biochemical Evolution?


Jane Flores

Biochemical evolution is a fascinating concept that has intrigued scientists for years. It refers to the process by which basic organic molecules evolved into more complex ones, eventually leading to the formation of life on Earth.

But who first proposed this theory and how did it come about? Let’s take a closer look.

The Beginnings of Biochemical Evolution

The idea of biochemical evolution can be traced back to the early 20th century when Russian biochemist Alexander Oparin proposed his theory on the origin of life. In his book “The Origin of Life,” published in 1924, Oparin suggested that life on Earth began as a result of chemical processes that occurred in the Earth’s early oceans.

Oparin believed that simple organic compounds such as amino acids and sugars could have formed spontaneously in the primitive atmosphere and ocean, eventually combining to create more complex molecules like proteins and nucleic acids. Over time, these molecules could have formed self-replicating structures, leading to the first living organisms.

The Miller-Urey Experiment

One of the most famous experiments supporting Oparin’s theory was conducted by American chemists Stanley Miller and Harold Urey in 1953. The Miller-Urey experiment simulated conditions thought to exist on early Earth by creating an atmosphere containing water vapor, methane, ammonia, and hydrogen.

By passing an electric current through this mixture, Miller and Urey were able to produce amino acids – the building blocks of proteins – suggesting that life could indeed have arisen from non-living matter through natural processes.

Modern Developments in Biochemical Evolution

Since Oparin’s original proposal and Miller-Urey experiment, our understanding of biochemical evolution has continued to evolve. Today we know that RNA – not DNA – may have been the first self-replicating molecule on Earth and that other factors such as hydrothermal vents and meteorite impacts may have played a role in the origin of life.

Furthermore, recent studies have shown that the process of biochemical evolution is ongoing, with new molecules and pathways evolving constantly.


In conclusion, the theory of biochemical evolution has its roots in the early 20th century with Alexander Oparin’s proposal on the origin of life. The Miller-Urey experiment provided further evidence for this theory, and modern developments continue to shed light on how life may have arisen from non-living matter. As our understanding of biochemistry and evolution continues to grow, it is likely that we will gain even more insight into this fascinating topic.